Alessandro Vindigni, PhD

Medical School Department Pathology and Immunology
Alessandro Vindigni

Researcher Background

Primary Academic Title

Professor of Medicine, Pathology and Immunology , WashU Medicine

Training

  • 1995 - 1999: Postdoctoral Fellow, WashU Medicine, St. Louis, MO

Education

  • 1995: PhD, Biochemistry and Molecular Biophysics, University of Padua, Padua, Italy

Research & Selected Publications

Research Interest

Aberrant DNA replication is one of the leading causes of mutations and chromosome rearrangements associated with several cancer related pathologies. At the same time, agents that stall or damage DNA replication forks are widely used for chemotherapy, in the attempt to selectively target highly proliferating cancer cells. Our group studies the mechanisms that operate in eukaryotic cells to maintain replication fork integrity upon chemical treatment with cancer chemotherapeutics.

Authors:

Seppa IM, Ceppi I, Tennakoon M, Vindigni A

Journal & Year:

Genes Dev • 2025

Authors:

Agashe S, Vindigni A

Journal & Year:

Trends Genet • 2025

Authors:

Cybulla E, Wallace S, Meroni A, Vindigni A

Journal & Year:

Nucleic Acids Res • 2024

Authors:

Ramakrishnan N, Weaver TM, Aubuchon LN, Vindigni A, Verma P

Journal & Year:

Nat Commun • 2024

Authors:

Meroni A, Wells SE, Fonseca C, Vindigni A

Journal & Year:

J Cell Biol • 2024

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