Charles Kaufman, MD, PhD

Medical Oncologist

Charles Kaufman

Appointment Options

Whether you’re seeking a new patient appointment or exploring treatment options and looking for a second opinion, our Siteman care coordinators are ready to assist you.

My Locations

Expertise & Training

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Charles Kaufman, MD, PhD

6 mins

Charles Kaufman, MD, PhD, a medical oncologist from the Siteman Cancer Center, discusses how great it is to meet patients for the first time when they are in a tough situation and be able to tell them that they have multiple treatment options with a very realistic probability of success.

Clinical Expertise

  • Melanoma, skin cancers

Primary Academic Title

Associate Professor of Medicine, Division of Medical Oncology, WashU Medicine

Board Certification

  • 2008: American Board of Internal Medicine
  • 2010: American Board of Internal Medicine - Medical Oncology

Training

  • 2005 - 2007: Resident, Internal Medicine, Brigham and Women's Hospital, Boston, MA
  • 2007 - 2011: Fellow, Hematology/Oncology, Dana-Farber Cancer Institute/Massachusetts General Cancer Center, Boston, MA
  • 2008 - 2016: Postdoctoral Research Fellow, Boston Children's Hospital, Boston, MA

Education

  • 2003: PhD, Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL
  • 2005: MD, University of Chicago, Chicago, IL

Research & Selected Publications

Research Interest

My goal as a physician-scientist is to interface between medicine and basic science to confront challenging fundamental questions in cancer biology. In particular, I study the molecular regulation of cancer initiation – the events that occur at the very start of tumor formation – during which cells readopt stem cell-like characteristics.

Research Publications

Mapping of the hSOX10 protein interactome in human melanoma
Authors:

Newsom-Stewart CM, Bhatt DP, Major MB, Kaufman CK

Journal & Year:

bioRxiv | 2025

Specific SOX10 enhancer elements modulate phenotype plasticity and drug resistance in melanoma
Authors:

DeGeorgia SN, Kaufman CK

Journal & Year:

bioRxiv | 2024

Dietary fructose enhances tumour growth indirectly via interorgan lipid transfer
Authors:

Fowle-Grider R, Rowles JL, Shen I, one or more additional authors omitted Kaufman CK, one or more additional authors omitted Patti GJ

Journal & Year:

Nature | 2024

Functional analysis of recurrent CDC20 promoter variants in human melanoma
Authors:

Godoy PM, Oyedeji A, Mudd JL, one or more additional authors omitted Kaufman CK

Journal & Year:

Commun Biol | 2023