Amit Pathak, PhD

Medical School Department Mechanical Engineering and Materials Science
Research Program Mechanisms of Cancer Biology Program
Amit Pathak

Researcher Background

Primary Academic Title

Professor, Department of Mechanical Engineering and Materials Science, WashU Medicine

Training

  • 2009 - 2012: Fellow, Bioengineering, University of California, Berkeley, CA

Education

  • 2008: PhD, biomechanics, University of California, Santa Barbara, CA

Research & Selected Publications

Research Interest

Tumor cells navigate the 3D tissue environment surrounding the primary tumor through physical cell-ECM interactions. However, the biophysical basis for this mechano-regulated tumor cell migration is not completely understood. This gap in knowledge remains due to a lack of in-vitro matrix scaffolds that permit controlled manipulation of various ECM parameters in cell culture scaffolds composed of soft ECMs that mimic tissue microenvironment.

Research Publications

Authors:

Shaji AT, Pathak A

Journal & Year:

Biophys J • 2026

Authors:

Yu H, Pathak A

Journal & Year:

Proc Natl Acad Sci USA • 2025

Authors:

Almeida JA, Avila DB, Longmore GD, Pathak A

Journal & Year:

Mol Biol Cell • 2025

Authors:

Lee YL, Longmore GD, Pathak A

Journal & Year:

Biophys J • 2025

Authors:

Lin WJ, Yu H, Pathak A

Journal & Year:

Soft Matter • 2025

Authors:

Bagchi A, Sarker B, Zhang J, Foston M, Pathak A

Journal & Year:

PLoS Comput Biol • 2025

Authors:

Zmuda H, Pathak A

Journal & Year:

FASEB J • 2023

Authors:

Lee YL, Mathur J, Walter C, Zmuda H, Pathak A

Journal & Year:

Mol Biol Cell • 2023

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