Researcher Background
Primary Academic Title
Professor of Medicine, Division of Oncology, Section of Molecular Oncology, Washington University School of Medicine
Training
- 1997 - 2001: Postdoctoral associate, Howard Hughes Medical Institute, St. Jude Children's Research Hospital, Memphis, TN
Education
- 1997: PhD, cell and molecular biology, Saint Louis University, St. Louis, MO
Research & Selected Publications
Research Interest
The p53 protein requires communication between upstream activators in order to sense when a cell is under stress. One such activator is the ARF tumor supressor. These two proteins are among the most frequently affected genes in human cancer. We are interested in understanding the individual contribution of these proteins to the development of human cancers and how they may be regulated by upstream signals.