Dimitrios Mathios, MD

Neurosurgeon

Dimitrios Mathios

Appointment Options

Whether you’re seeking a new patient appointment or exploring treatment options and looking for a second opinion, our Siteman care coordinators are ready to assist you.

My Locations

Gary C. Werths Building at Siteman Cancer Center

Gary C. Werths Building at Siteman Cancer Center

On WashU Medicine Campus
4500 Forest Park Avenue, Saint Louis, MO 63108

Expertise & Training

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Dr. Dimitrios Mathios, MD

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Dr. Dimitrios Mathios, MD Assistant Professor of Neurosurgery, Washington University School of Medicine at Siteman Cancer Center

Clinical Expertise

  • Neurosurgical Oncology

Primary Academic Title

Assistant Professor of Neurosurgery, WashU Medicine

Training

  • 2011 - 2015: Postdoctoral Research Fellow, Johns Hopkins University School of Medicine, Baltimore MD
  • 2015 - 2022: Neurosurgery Resident, Johns Hopkins University School of Medicine, Baltimore, MD

Education

  • 2011: MD, Kapodistrian University of Athens School of Medicine, Athens, Greece

Research & Selected Publications

Research Interests

Clinical: Brain tumors Research interest: Genetics and Epigenetic, immunotherapy, liquid biopsy

Research Publications

Cell-free DNA fragmentomes for noninvasive detection of liver cirrhosis and other diseases
Authors:

Annapragada AV, Foda ZH, Orjuela H, one or more additional authors omitted Mathios D, one or more additional authors omitted Velculescu VE

Journal & Year:

Sci Transl Med | 2026

Diffusely metastatic glioblastoma with FGFR3::TACC3 fusion: cell-free DNA fragmentation analyses and molecular characterization of matched primary and metastatic tumor sites
Authors:

Hernandez-Rovira MA, Vagnozzi A, Bales T, one or more additional authors omitted Mathios D

Journal & Year:

Acta Neuropathol Commun | 2025

Detection of Brain Cancer Using Genome-wide Cell-free DNA Fragmentomes
Authors:

Mathios D, Niknafs N, Annapragada AV, one or more additional authors omitted Velculescu VE

Journal & Year:

Cancer Discov | 2025

Case report: Molecular characterization of adult atypical teratoid rhabdoid tumor and review of the literature
Authors:

Hernandez-Rovira MA, Connor M, Osorio RC, one or more additional authors omitted Mathios D

Journal & Year:

Front Oncol | 2025

Tumor-informed deep sequencing of ctDNA detects minimal residual disease and predicts relapse in osteosarcoma
Authors:

Fu Y, Xu Y, Liu W, one or more additional authors omitted Mathios D, one or more additional authors omitted Yin J

Journal & Year:

EClinicalMedicine | 2024

Innovation in Non-Invasive Diagnosis and Disease Monitoring for Meningiomas
Authors:

Korte B, Mathios D

Journal & Year:

Int J Mol Sci | 2024