Ting Wang, PhD

Academic Department Genetics
Research Program Solid Tumor Therapeutics
Ting Wang

Researcher Background

Primary Academic Title

Professor of Genetics, WashU Medicine

Training

  • 2006 - 2009: Postdoctoral Fellow, Computational Biology, University of California, Santa Cruz, CA

Education

  • 2001: MS, Computer Sciences, Washington University, St. Louis, MO
  • 2006: PhD, Computational Biology, Washington University, St. Louis, MO

Research & Select Publications

Research Interest

Computational genomics and epigenomics. The evolution and adaption of human regulatory networks, with a focus on mobile elements (i.e., transposable elements) and their impact on gene regulation, their genetic and epigenetic control, and their roles in human biology and diseases. In particular, we are studying how DNA methylation changes in transposable elements influence tumorigenesis.

Research Publications

Accelerating discovery of cancer causes for prevention in the era of rising early-onset cancers.
Authors:

Shi M, Patti GJ, Gunter MJ, one or more additional authors omitted Wang T, one or more additional authors omitted Cao Y

Journal & Year:

Cell • 2026

Fully T2T pedigree assemblies reveal genetic stability and epigenetic plasticity of human centromeres across inheritance and cell-fate transitions.
Authors:

Dong S, Xing X, Cechova M, one or more additional authors omitted Wang T

Journal & Year:

bioRxiv • 2026

Leveraging Human Pangenome for Improved Somatic Variant Detection.
Authors:

Fu Q, Xin Z, Miao B, one or more additional authors omitted Wang T

Journal & Year:

bioRxiv • 2026

An integrated view of the structure and function of the human 4D nucleome.
Authors:

Dekker J, Oksuz BA, Zhang Y, one or more additional authors omitted Wang T, one or more additional authors omitted Yue F

Journal & Year:

Nature • 2026

Unmasked: transposable elements as drivers and targets in cancer.
Authors:

Grinwald MF, Saintilnord WN, Wang T

Journal & Year:

Trends Genet • 2026

INSM1 governs a neuronal progenitor state that drives glioblastoma in a human stem cell model.
Authors:

DeSouza PA, Ishahak M, Qu X, one or more additional authors omitted Wang T, one or more additional authors omitted Kim AH

Journal & Year:

Nat Commun • 2025

Cross-tissue molecular responses in the liver and blood after toxicant exposures.
Authors:

Zhang B, Miao B, Fu S, one or more additional authors omitted Wang T

Journal & Year:

Res Sq • 2025

Non-canonical functions of DNMT3A in hematopoietic stem cells regulate telomerase activity and genome integrity.
Authors:

Xavier Raj I, Kyun Koh W, Harrison J, one or more additional authors omitted Wang T, one or more additional authors omitted Challen GA

Journal & Year:

Cell Stem Cell • 2025

The impact of environmental exposures on the epigenomic and transcriptomic landscape of transposable elements.
Authors:

Miao B, Zhang Y, Shao W, one or more additional authors omitted Wang T

Journal & Year:

bioRxiv • 2025

The Somatic Mosaicism across Human Tissues Network.
Authors:

Coorens THH, Oh JW, Choi YA, one or more additional authors omitted Wang T, one or more additional authors omitted Vaccarino FM

Journal & Year:

Nature • 2025

Charting the regulatory landscape of TP53 on transposable elements in cancer.
Authors:

Qu X, Liang Y, McCornack C, one or more additional authors omitted Wang T

Journal & Year:

Genome Res • 2025

Transcriptional and chromatin accessibility landscapes of hematopoiesis in a mouse model of breast cancer.
Authors:

Fan C, Wu J, Barisas DAG, one or more additional authors omitted Wang T

Journal & Year:

J Immunol • 2025

Exploring the epigenome profiles of repetitive elements with the WashU Repeat Browser.
Authors:

Shen J, Cheng S, Purushotham D, one or more additional authors omitted Wang T

Journal & Year:

Genome Res • 2025

iPSCs and iPSC-derived cells as a model of human genetic and epigenetic variation.
Authors:

Quaid K, Xing X, Chen YH, one or more additional authors omitted Wang T

Journal & Year:

Nat Commun • 2025

Epigenetic therapy potentiates transposable element transcription to create tumor-enriched antigens in glioblastoma cells.
Authors:

Jang HJ, Shah NM, Maeng JH, one or more additional authors omitted Wang T

Journal & Year:

Nat Genet • 2024