Bhuvic Patel, MD

Neurosurgeon

Bhuvic Patel

Appointment Options

Whether you’re seeking a new patient appointment or exploring treatment options and looking for a second opinion, our Siteman care coordinators are ready to assist you.

My Locations

Gary C. Werths Building at Siteman Cancer Center

Gary C. Werths Building at Siteman Cancer Center

On WashU Medicine Campus
4500 Forest Park Avenue, Saint Louis, MO 63108

Expertise & Training

Video thumbnail for Bhuvic Patel, MD

Watch video on YouTube

Bhuvic Patel, MD

7 mins

Bhuvic Patel, MD Neurosurgeon from Siteman Cancer Center discusses why patients should consider Siteman for their cancer care. He emphasizes that Siteman offers a comprehensive approach, brining together experts from every specialty to address every type of cancer. Whether a patient needs surgery, radiation, therapy, or a combination of solutions, Siteman has the right specialist ready to deliver personalized care.

Clinical Expertise

  • Skull base neurosurgery

Primary Academic Title

Assistant Professor of Neurosurgery, Division of Cranial Surgery; Surgical Director, Pituitary Center, WashU Medicine

Training

  • 2015 - 2022: Neurological Surgery Residency, WashU Medicine, St. Louis, MO
  • 2019 - 2021: Postdoctoral Research Fellowship, WashU Medicine, St. Louis, MO
  • 2022 - 2023: Postdoctoral Research Fellowship, German Cancer Research Center, Heidelberg, Germany
  • 2023 - 2024: Skull Base Neurosurgery Fellowship, University of Pittsburgh Medical Center, Pittsburgh, PA

Education

  • 2011: BS, Brown University, Providence, RI
  • 2015: MD, WashU Medicine, St. Louis, MO

Research & Selected Publications

Research Interest

My laboratory focuses on complex skull base tumors, including pituitary adenomas, meningiomas, and vestibular schwannomas—tumors I frequently encounter in the operating room. We employ advanced molecular techniques like single-cell RNA sequencing, high-resolution spatial transcriptomics, and epigenetic profiling to dissect these tumors at a cellular level. By integrating these data, we aim to unravel the mechanisms driving aggressive tumor behavior and develop novel therapies for tumors resistant to conventional treatments. Our goal is to personalize treatment strategies, improving outcomes for patients with these challenging and often refractory tumors.

Research Publications

Single-cell multi-omic techniques highlight the diverse composition and intercellular interactions of the vestibular schwannoma tumor microenvironment
Authors:

Pari SS, Pugazenthi S, Kim AH, Patel B

Journal & Year:

Neurooncol Adv | 2026

NF2 loss-of-function and hypoxia drive radiation resistance in grade 2 meningiomas
Authors:

Patel B, Pugazenthi S, English CW, one or more additional authors omitted Kim AH

Journal & Year:

J Natl Cancer Inst | 2025

Spatially resolved transcriptomics and graph-based deep learning improve accuracy of routine CNS tumor diagnostics
Authors:

Ritter M, Blume C, Tang Y, one or more additional authors omitted Patel B, one or more additional authors omitted Sahm F

Journal & Year:

Nat Cancer | 2025

The evolution and application of multi-omic analysis for pituitary neuroendocrine tumors
Authors:

Pugazenthi S, Pari SS, Zhang Z, one or more additional authors omitted Patel B

Journal & Year:

Front Med (Lausanne) | 2025

Multiomic and clinical analysis of multiply recurrent meningiomas reveals risk factors, underlying biology, and insights into evolution
Authors:

Pugazenthi S, Patel B, English CW, one or more additional authors omitted Kim AH

Journal & Year:

Sci Adv | 2024

Single-cell multi-omic analysis of the vestibular schwannoma ecosystem uncovers a nerve injury-like state
Authors:

Barrett TF, Patel B, Khan SM, one or more additional authors omitted Kim AH

Journal & Year:

Nat Commun | 2024

Cranial Nerve IX and X Neurectomy for Glossopharyngeal Neuralgia: Case Report and Operative Video
Authors:

Patel B, Pugazenthi S, Dowling J

Journal & Year:

Neurosurg Pract | 2023