Daniel Link, MD

Medical School Department Internal Medicine
Research Program Hematopoietic Development & Malignancy
Dan Link

Researcher Background

Daniel C. Link, MD

4 mins

Daniel C. Link, MD, deputy director of Siteman Cancer Center and a WashU Medicine medical oncologist, discusses advances in the understanding and treatment of blood cancers, including leukemia.

Dr. Link shares insight into the research behind these diseases and how discoveries in cancer biology and genetics are helping physicians develop more precise, effective approaches to treatment and improve care for patients with blood cancers.

Primary Academic Title

Deputy Director, Alvin J. Siteman Cancer Center; Chief, Division of Oncology; Alan A. and Edith L. Wolff Professor of Medicine, Division of Oncology, WashU Medicine

Training

  • 1985 - 1988: Intern and Resident, Internal Medicine, WashU Medicine, St. Louis, MO
  • 1988 - 1992: Fellow, Hematology/Oncology, WashU Medicine, St. Louis, MO

Education

  • 1985: MD, University of Wisconsin, Madison, WI

Research & Selected Publications

Research Interest

Molecular mechanisms controlling hematopoietic cell proliferation and differentiation; granulocyte colony stimulating factor receptor signal transduction and biological activities

Research Publications

Synthetic lethality of decitabine plus ATR inhibition for TP53-mutated AML.
Authors:

Baeten JT, Agashe S, Tabet I, one or more additional authors omitted Link DC

Journal & Year:

Blood Adv • 2026

A clinical guide to TP53 mutations in myeloid neoplasms.
Authors:

Urrutia S, Wong TN, Link DC

Journal & Year:

Blood • 2025

Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy.
Authors:

Liu J, Tran D, Xue L, one or more additional authors omitted Link DC, one or more additional authors omitted Bolton KL

Journal & Year:

Nat Genet • 2025

How chemotherapy shapes hematopoietic stem cells.
Authors:

Wong TN, Link DC

Journal & Year:

Nat Genet • 2025

ATM-dependent DNA damage response constrains cell growth and drives clonal hematopoiesis in telomere biology disorders.
Authors:

Sande CM, Chen S, Mitchell DV, one or more additional authors omitted Link DC, one or more additional authors omitted Babushok DV

Journal & Year:

J Clin Invest • 2025

Are TP53 mutations all alike?
Authors:

Wong TN, Link DC

Journal & Year:

Hematology Am Soc Hematol Educ Program • 2024

The Clonal Hematopoiesis-associated Gene Srcap Plays an Essential Role in Hematopoiesis.
Authors:

Wong TN, Mychalowych A, Feldpausch ER, one or more additional authors omitted Link DC

Journal & Year:

bioRxiv • 2024

Plasma Proteomic Signature Predicts Myeloid Neoplasm Risk.
Authors:

Tran D, Beeler JS, Liu J, one or more additional authors omitted Link DC, one or more additional authors omitted Bolton KL

Journal & Year:

Clin Cancer Res • 2024