Gautam Dantas, PhD

Medical School Department Pathology and Immunology
Gautam Dantas

Researcher Background

Primary Academic Title

Conan Professor of Laboratory and Genomic Medicine

Training

  • 2009: Postdoctoral Fellowship: Genetics, Harvard Medical School, Boston, MA

Education

  • 2000: BA, with honors: Biology and Chemistry, Macalester College, St. Paul, MN
  • 2005: PhD: Biochemistry, University of Washington, Seattle, WA

Research & Selected Publications

Research Interest

Dr. Dantas’s research interests and training lie at the interface of microbial genomics, synthetic biology, systems biology, and computational biology. His current research focuses on understanding (1) the evolution and exchange of antibiotic resistance amongst diverse microbial communities, (2) on engineering improved probiotics to treat gastrointestinal disorders, and (3) on engineering microbial catalysts to produce value chemicals such as biofuels.

Research Publications

A Novel Focal Duodenal Radiation Injury Model Reveals Dose-, Time-, and Spatially Dependent Microbiome Perturbations After Radiation Injury.
Authors:

Habimana-Griffin L, Prusa J, Wang B, one or more additional authors omitted Dantas G

Journal & Year:

Int J Radiat Oncol Biol Phys • 2026

State of omics-based microbial diagnostics of CRC.
Authors:

Prusa J, Gorelik MG, Blake KS, Dantas G

Journal & Year:

Gut Microbes • 2025

A yeast-based oral therapeutic delivers immune checkpoint inhibitors to reduce intestinal tumor burden.
Authors:

Rebeck ON, Wallace MJ, Prusa J, one or more additional authors omitted Dantas G

Journal & Year:

Cell Chem Biol • 2025

Genomic surveillance of Clostridioides difficile transmission and virulence in a healthcare setting.
Authors:

Newcomer EP, Fishbein SRS, Zhang K, one or more additional authors omitted Dantas G

Journal & Year:

medRxiv • 2023