Hong Chen, PhD

Medical School Department Biomedical Engineering
Research Program Oncologic Imaging
Hong Chen

Researcher Background

Primary Academic Title

Associate Professor of Biomedical Engineering

Training

  • 2011 - 2012: Senior Fellow, University of Washington, Seattle, WA

Education

  • 2011: PhD, Bioengineering, University of Washington, Seattle, WA

Research & Selected Publications

Research Interest

Ultrasound, one of the most widely used medical imaging modalities, is currently being developed as a noninvasive, targeted therapeutic technique that has incredible potential to transform the treatment of cancer. Prof. Hong Chen’s research focuses on translating basic research advances in ultrasound imaging and therapy into image-guided therapy devices that can impact cancer patient care.

Research Publications

Focused ultrasound-enhanced nose-to-brain delivery of a therapeutic antibody in a large-animal model.
Authors:

Fadera S, Boas CAWV, Yue Y, one or more additional authors omitted Chen H

Journal & Year:

Theranostics • 2026

Intranasal versus intravenous AAV delivery: A comparative analysis of brain-targeting efficiency and peripheral exposure in mice.
Authors:

Chukwu C, Yuan J, Chen H

Journal & Year:

Gene Ther • 2025

Noninvasive enrichment of circulating tumor biomarkers in a mouse model of diffuse midline glioma using focused ultrasound.
Authors:

Zhang D, Yue Y, Gong Y, one or more additional authors omitted Chen H

Journal & Year:

bioRxiv • 2025

Synthetic torpor: advancing metabolic regulation for medical innovations.
Authors:

Wu W, Sunagawa GA, Chen H

Journal & Year:

Nat Metab • 2025

In vivo two-photon microscopy imaging of focused ultrasound-mediated glymphatic transport in the mouse brain.
Authors:

Gong Y, Xu K, Ye D, one or more additional authors omitted Chen H

Journal & Year:

J Cereb Blood Flow Metab • 2025

Sonobiopsy for sensitive and spatially targeted molecular diagnosis through integrating ultrasound with liquid biopsy.
Authors:

Yuan J, Chen H

Journal & Year:

NPJ Acoust • 2025

Adeno-associated virus vector delivery to the brain: Technology advancements and clinical applications.
Authors:

Ye D, Chukwu C, Yang Y, Hu Z, Chen H

Journal & Year:

Adv Drug Deliv Rev • 2024

Airy-beam holographic sonogenetics for advancing neuromodulation precision and flexibility.
Authors:

Hu Z, Yang Y, Yang L, one or more additional authors omitted Chen H

Journal & Year:

Proc Natl Acad Sci USA • 2024