Julie Margenthaler, MD, FACS

Surgeon

Julie Margenthaler

Appointment Options

Whether you’re seeking a new patient appointment or exploring treatment options and looking for a second opinion, our Siteman care coordinators are ready to assist you.

My Locations

Gary C. Werths Building at Siteman Cancer Center

Gary C. Werths Building at Siteman Cancer Center

On WashU Medicine Campus
4500 Forest Park Avenue, Saint Louis, MO 63108
Siteman Cancer Center at Barnes-Jewish West County Hospital

Siteman Cancer Center at Barnes-Jewish West County Hospital

Medical Office Building 2, 10 Barnes West Drive, Creve Coeur, MO 63141

Expertise & Training

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Julie Margenthaler, MD, FACS

2 mins

Washington University surgeon Julie Margenthaler, MD, FACS, discusses what breast cancer patients can expect from their extended care team at Siteman Cancer Center. Learn more about Dr. Margenthaler: https://siteman.wustl.edu/doctor/margenthaler-julie/

Learn more about the Siteman Approach to Breast Cancer: https://siteman.wustl.edu/treatment/cancer-types/breast-cancer/our-approach/

Learn more about all breast cancer treatment options at Siteman Cancer Center: https://siteman.wustl.edu/treatment/cancer-types/breast-cancer/treatments/

Hear from Siteman patients who discuss their journey with breast cancer diagnosis, treatment and recovery: https://siteman.wustl.edu/treatment/cancer-types/breast-cancer/patient-stories/

Clinical Expertise

Primary Academic Title

Professor of Surgery, Division of General Surgery, Section of Endocrine and Oncologic Surgery, WashU Medicine

Board Certification

  • 2006: American Board of Surgery, General Surgery

Training

  • 1997 - 1999: Resident, General Surgery, Saint Louis University, St. Louis, MO
  • 1999 - 2002: Research Fellow, WashU Medicine, St. Louis, MO
  • 2002 - 2005: Resident, General Surgery, WashU Medicine, St. Louis, MO
  • 2005 - 2006: Fellow, Surgical Oncology, WashU Medicine, St. Louis, MO

Education

  • 1997: MD, Southern Illinois University, Springfield, IL

Research & Selected Publications

Research Interest

Identification of minimally invasive approaches to breast cancer staging using imaging combined with molecular techniques; the identification of non-BRCA genes responsible for the development of breast cancer in young women under the age of 40; and the design of novel gene-specific approaches to breast cancer treatment.

Research Publications

Evaluating Factors Associated with Advanced-Stage Breast Cancer Presentation in Rural Patients in the National Cancer Database
Authors:

Sogade OO, Margenthaler JA

Journal & Year:

J Am Coll Surg | 2026

Biomarkers of response to neoadjuvant palbociclib plus anastrozole in endocrine-resistant estrogen receptor-positive/HER2-negative breast cancer: a phase 2 trial
Authors:

Kong T, Mabry A, Highkin M, one or more additional authors omitted Margenthaler J, one or more additional authors omitted Ma CX

Journal & Year:

Nat Commun | 2026

ASO Visual Abstract: Impact of Sociodemographic and Clinical Factors on Postoperative Outcomes Following Immediate Post-mastectomy Autologous Breast Reconstruction
Authors:

Naaseh A, Bewley AF, Nickel KB, Myckatyn TM, Margenthaler JA

Journal & Year:

Ann Surg Oncol | 2026

Impact of Sociodemographic and Clinical Factors on Postoperative Outcomes Following Immediate Postmastectomy Autologous Breast Reconstruction
Authors:

Naaseh A, Bewley AF, Nickel KB, Myckatyn TM, Margenthaler JA

Journal & Year:

Ann Surg Oncol | 2026

Feasibility and Efficacy of Decision Aids to Improve Decision-Making for Contralateral Prophylactic Mastectomy: A Systematic Review
Authors:

Naaseh A, Tang SX, Lipsey KL, Politi MC, Margenthaler JA

Journal & Year:

Ann Surg Oncol | 2025

Are Broadened Guidelines Improving our Detection of Pathologic Genetic Mutations in Breast Cancer Patients? A 5-Year Comparative Analysis of American Society of Breast Surgeons and…
Authors:

Naaseh A, Tang SX, Maytin-Hevia AR, Wu N, Margenthaler JA

Journal & Year:

Ann Surg Oncol | 2025

ASO Visual Abstract: Are Broadened Guidelines Improving Our Detection of Pathologic Genetic Mutations in Breast Cancer Patients? A 5-Year Comparative Analysis of American Society o…
Authors:

Naaseh A, Tang SX, Maytin-Hevia AR, Wu N, Margenthaler JA

Journal & Year:

Ann Surg Oncol | 2025

Recurrence Risk in Young Women With Breast Cancer
Authors:

Margenthaler JA

Journal & Year:

JAMA Surg | 2025