Omar Butt, MD, PhD, MS

Medical Oncologist, Neuro-Oncologist

Omar Butt

Appointment Options

Whether you’re seeking a new patient appointment or exploring treatment options and looking for a second opinion, our Siteman care coordinators are ready to assist you.

My Locations

Gary C. Werths Building at Siteman Cancer Center

Gary C. Werths Building at Siteman Cancer Center

On WashU Medicine Campus
4500 Forest Park Avenue, Saint Louis, MO 63108

Expertise & Training

Clinical Expertise

  • Neuro-Oncology

Primary Academic Title

Assistant Professor of Medicine, Division of Oncology, WashU Medicine

Board Certification

  • 2020: American Board of Psychiatry and Neurology

Training

  • 2020 - 2022: Fellow, Neuro-Oncology, WashU Medicine, St. Louis, MO

Education

  • 2007: MS, Johns Hopkins University, Baltimore, MD
  • 2014: PhD, Neuroscience, University of Pennsylvania, Philadelphia, PA
  • 2016: MD, University of Pennsylvania, Philadelphia, PA

Research & Selected Publications

Research Interest

CNS toxicity and understanding the mechanisms of underlying neurotoxicity after cellular therapy

Research Publications

Adjuvant personalized multivalent neoantigen DNA vaccination for MGMT unmethylated glioblastoma: a phase 1 trial
Authors:

Garfinkle EAR, Perales-Linares R, Gimple RC, one or more additional authors omitted Butt OH, one or more additional authors omitted Johanns TM

Journal & Year:

Nat Cancer | 2026

Evaluation of Regorafenib in Newly Diagnosed and Recurrent Glioblastoma: GBM AGILE Phase II/III Bayesian Randomized Platform Trial
Authors:

Wen PY, Berry DA, Buxton MB, one or more additional authors omitted Butt OH, one or more additional authors omitted Lassman AB

Journal & Year:

J Clin Oncol | 2026

Laser interstitial thermal therapy and adjuvant pembrolizumab in recurrent high-grade astrocytoma: a Phase 1/randomized Phase 2b trial
Authors:

Campian JL, Le SB, Ghiaseddin A, Butt OH, one or more additional authors omitted Tran DD

Journal & Year:

Nat Commun | 2026

Evolving Barriers to Clinical Trial Enrollment and Clinical Care in Neuro-oncology in the Face of COVID-19
Authors:

Grandhi N, Zhou AY, Johnson MO, Butt OH

Journal & Year:

Semin Neurol | 2024

BRAF/MEK Inhibition as a Bridge to Immunotherapy for Symptomatic BRAF V600 Melanoma Brain Metastases: A Case Series
Authors:

Strelnikov J, Zhou A, Butt O, Ansstas M , Ansstas G

Journal & Year:

J Natl Compr Canc Netw | 2023