Ron Bose, MD, PhD

Medical Oncologist

Ron Bose

Appointment Options

Whether you’re seeking a new patient appointment or exploring treatment options and looking for a second opinion, our Siteman care coordinators are ready to assist you.

My Locations

Siteman Cancer Center at Barnes-Jewish West County Hospital

Siteman Cancer Center at Barnes-Jewish West County Hospital

Medical Office Building 2, 10 Barnes West Drive, Creve Coeur, MO 63141

Expertise & Training

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Ron Bose, MD, PhD

3 mins

Washington University medical oncologist Ron Bose, MD, PhD, discusses what breast cancer patients can expect from their extended care team at Siteman Cancer Center. Learn more about Dr. Bose: https://siteman.wustl.edu/doctor/bose-ron/

Learn more about the Siteman Approach to Breast Cancer: https://siteman.wustl.edu/treatment/cancer-types/breast-cancer/our-approach/

Learn more about all breast cancer treatment options at Siteman Cancer Center: https://siteman.wustl.edu/treatment/cancer-types/breast-cancer/treatments/

Hear from Siteman patients who discuss their journey with breast cancer diagnosis, treatment and recovery: https://siteman.wustl.edu/treatment/cancer-types/breast-cancer/patient-stories/

Clinical Expertise

  • Breast Cancer

Primary Academic Title

Associate Professor of Medicine, Division of Oncology, WashU Medicine

Board Certification

  • 2002: American Board of Internal Medicine, Internal Medicine
  • 2004: American Board of Internal Medicine, Medical Oncology

Training

  • 1999 - 2002: Intern and Resident, Internal Medicine, WashU Medicine, St. Louis, MO
  • 2002 - 2007: Fellow, Medical Oncology, Johns Hopkins University, Baltimore, MD

Education

  • 1998: PhD, Pharmacology and Biochemistry, Cornell University, New York, NY
  • 1999: MD, Cornell University, New York, NY

Research & Selected Publications

Research Interest

HER2-positive breast cancer is a subtype of breast cancer where the HER2/neu tyrosine kinase drives the proliferation of cancer cells by activating a biochemical signaling pathway. We study this pathway using the techniques of proteomics and mass spectometry, coupled with traditional biochemistry and cell biology approaches.

Research Publications

Biomarkers of response to neoadjuvant palbociclib plus anastrozole in endocrine-resistant estrogen receptor-positive/HER2-negative breast cancer: a phase 2 trial
Authors:

Kong T, Mabry A, Highkin M, one or more additional authors omitted Bose R, one or more additional authors omitted Ma CX

Journal & Year:

Nat Commun | 2026

ctDNA Analysis in ERBB2-Amplified Colorectal Cancer: Biomarker Analysis of the MyPathway Trial
Authors:

Meric-Bernstam F, Raghav KPS, Sweeney CJ, one or more additional authors omitted Bose R, one or more additional authors omitted Kurzrock R

Journal & Year:

Clin Cancer Res | 2025

HER2; p53 Co-mutated Cancers Show Increased Histone Acetylation and are Sensitive to Neratinib plus Trastuzumab Deruxtecan
Authors:

Cheng X, Hsia J, Iraheta J, one or more additional authors omitted Bose R

Journal & Year:

bioRxiv | 2025

Cerebellum metastasis model of HER2-positive breast cancer unveils key role of IL34-induced Arg1+ macrophages
Authors:

Cheng X, Patel KK, Zhou B, one or more additional authors omitted Bose R

Journal & Year:

bioRxiv | 2025

Detection of Circulating Tumor DNA Using a Tissue-Free Epigenomic Assay Is a Highly Prognostic Biomarker in Early-Stage Triple-Negative Breast Cancer
Authors:

Ademuyiwa FO, Ma CX, Weilbaecher K, one or more additional authors omitted Bose R, one or more additional authors omitted Davis A

Journal & Year:

Clin Cancer Res | 2025

Sacituzumab-govitecan-induced severe acute tubulointerstitial nephritis requiring hemodialysis
Authors:

Guarin G, Netzel A, Flores KM, Cumpelik A, Bose R

Journal & Year:

BMC Nephrol | 2024

Adjuvant Trastuzumab Emtansine Versus Paclitaxel Plus Trastuzumab for Stage I Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: 5-Year Results and Correlative Analys…
Authors:

Tarantino P, Tayob N, Villacampa G, one or more additional authors omitted Bose R, one or more additional authors omitted Tolaney SM

Journal & Year:

J Clin Oncol | 2024

Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages
Authors:

Iglesia MD, Jayasinghe RG, Chen S, one or more additional authors omitted Bose R, one or more additional authors omitted Ding L

Journal & Year:

Nat Cancer | 2024