Researcher Background
Primary Academic Title
Assistant Professor, Division of Oncology, WashU Medicine
Training
- 2003 - 2008: Postdoctoral Fellow, Department of Physics , University of Missouri-Columbia, Columbia, MO
- 2008 - 2011: Research Associate, Department of Physics, University of Missouri-Columbia, Columbia, MO
Education
- 2003: PhD, Zhejiang University, Hangzhou,, China
Research & Selected Publications
Research Interest
My research interests include cancer virology, cancer genomics, and cancer proteomics. I have a deep understanding of various omics data types, including DNA-Seq, RNA-Seq, scRNA-Seq, and mass spectrometry data. I have led the development of multiple bioinformatics tools and pipelines, such as VirusScan for virus detection from NGS data, Misplice tool for detecting splice-site-creating mutations, somaticwrapper and germlinewrapper pipelines for calling somatic and germline variants, and among others. My long-term goal is to discover rational therapeutic targets that meaningfully impact the lives of cancer patients. For instance, by working with CPTAC members, I uncovered high PTPN11 Y62 phosphorylation in EGFR-altered brain and lung tumors.
Research Publications