News & Breakthroughs at Siteman
Stay informed with the latest cancer news and breakthroughs from Siteman Cancer Center. Our news feed provides timely updates on research breakthroughs, clinical trials, and community events.
Research News & Stories
Research
New insight into origin of stomach cancer
Conventional wisdom holds that the loss of cells that secrete acid in the stomach leads to a condition that eventually can develop into stomach cancer. But new research at Washington University School of Medicine and Siteman Cancer Center at Barnes-Jewish Hospital and Washington University in St. Louis indicates otherwise. Researchers found that damage to acid-secreting […]
Research
Immunotherapy for newly diagnosed endometrial cancer
For the first time ever, investigators are studying immunotherapy for patients with newly diagnosed endometrial cancer. The trial uses pembrolizumab, a programmed death receptor-1 (PD-1) inhibitor. The drug is currently approved by the Food and Drug Administration for treatment of advanced melanoma and metastatic non-small-cell lung cancer. “Pembrolizumab has been studied in patients with relapsed […]
Research
Study unveils new way to starve tumors to death
For decades, scientists have tried to halt cancer by blocking nutrients from reaching tumor cells, in essence starving tumor cells of the fuel needed to grow and proliferate. Such attempts often have disappointed because cancer cells are nimble, relying on numerous backup routes to continue growing. Now, scientists at Washington University School of Medicine in […]
Research
In highly lethal type of leukemia, cancer gene predicts treatment response
Patients with the most lethal form of acute myeloid leukemia (AML) – based on genetic profiles of their cancers – typically survive for only four to six months after diagnosis, even with aggressive chemotherapy. But new research indicates that such patients, paradoxically, may live longer if they receive a milder chemotherapy drug. Treatment with the […]
Research
Pathway linked to slower aging also fuels brain cancer
While a particular metabolic pathway shows potential to slow down the aging process, new research indicates a downside: That same pathway may drive brain cancer. The pathway, known as the nicotinamide adenine dinucleotide (NAD+) pathway, is overactive in a deadly form of brain cancer known as glioblastoma, according to a study by researchers at Washington […]
Research
Weight loss may help prevent multiple myeloma
New research shows that excess weight increases the risk that a benign blood disorder will progress into multiple myeloma, a cancer of the blood. The study, by a team at Washington University School of Medicine in St. Louis, is published Nov. 18 in the Journal of the National Cancer Institute. Being overweight or obese has […]
Research
New topical immunotherapy effective against early skin cancer
A combination of two topical drugs that have been in use for years triggers a robust immune response against precancerous skin lesions, according to a new study. The research, from Washington University School of Medicine in St. Louis and Harvard Medical School, shows that the therapy activates the immune system’s T cells, which then attack […]
Research
Siteman fund grants $300,000 for unique approaches to fighting cancer
Two scientists at Washington University School of Medicine in St. Louis and Siteman Cancer Center will receive a combined $300,000 in funding over two years for their innovative approaches to fighting cancer. The awards, from the Alvin J. Siteman Cancer Research Fund, are meant to further promising early-stage science that because of its unconventional approach […]
Research
$10.4 million awarded for pancreatic cancer research
The National Cancer Institute (NCI) has awarded a $10.4 million, five-year grant to Washington University researchers and physicians at Siteman Cancer Center to lead a national group of experts in collaborative pancreatic cancer research. The award, a prestigious Specialized Program of Research Excellence (SPORE) grant, will help scientists pursue new treatments for the deadliest form […]
Research
Even with genetic predisposition for lung cancer, quitting smoking reduces risk
Quitting smoking improves health and lowers odds of developing lung cancer. But a new study shows that even among smokers with a genetic predisposition to smoking heavily and developing lung cancer at a young age, the benefits of quitting are significant. An international study led by researchers at Washington University School of Medicine in St. […]