News & Breakthroughs at Siteman
Stay informed with the latest cancer news and breakthroughs from Siteman Cancer Center. Our news feed provides timely updates on research breakthroughs, clinical trials, and community events.
Research News & Stories
Research
Major milestone reached in effort to ID cancers’ genetic roots
Researchers nationwide have reached a major milestone in describing the genetic landscape of cancer. Scientists at Washington University School of Medicine in St. Louis and other institutions have completed the genetic sequencing and analyses of more than 11,000 tumors from patients, spanning 33 types of cancer — all part of The Cancer Genome Atlas (TCGA) […]
Research
Experimental arthritis drug prevents stem cell transplant complication
An investigational drug in clinical trials for rheumatoid arthritis prevents a common, life-threatening side effect of stem cell transplants, new research from Washington University School of Medicine in St. Louis shows. Studying mice, the researchers found the drug prevented what’s known as graft-versus-host disease, a debilitating, sometimes lethal condition that develops when transplanted stem cells […]
Research
CRISPR enhances cancer immunotherapy
Last year, the Food and Drug Administration approved the first cellular immunotherapies to treat cancer. These therapies involve collecting a patient’s own immune cells — called T cells — and supercharging them to home in on and attack specific blood cancers, such as hard-to-treat acute lymphoblastic leukemia and non-Hodgkin lymphoma. But so far, these T […]
Research
Higher doses of radiation don’t improve survival in prostate cancer
A new study shows that higher doses of radiation do not improve survival for many patients with prostate cancer, compared with the standard radiation treatment. The analysis, which included 104 radiation therapy oncology groups across North America, was led by researchers at Washington University School of Medicine in St. Louis. Past studies have shown that […]
Research
Cutting off cervical cancer’s fuel supply stymies tumor
Cancer therapies have improved — in some cases dramatically — over the past two decades, but treatment for cervical cancer has remained largely unchanged. All patients receive radiation and chemotherapy, yet despite the aggressive approach, the regimen fails in about one-third of patients with cervical cancer that has spread beyond the cervix but not outside […]
Research
Similarities found in cancer initiation in kidney, liver, stomach, pancreas
Recent research at Washington University School of Medicine in St. Louis demonstrated that mature cells in the stomach sometimes revert back to behaving like rapidly dividing stem cells. Now, the researchers have found that this process may be universal; no matter the organ, when tissue responds to certain types of injury, mature cells seem to […]
Research
Light-triggered nanoparticles show promise against metastatic cancer
A new anti-cancer strategy wields light as a precision weapon. Unlike traditional light therapy — which is limited to the skin and areas accessible with an endoscope — this technique can target and attack cancer cells that have spread deep inside the body, according to researchers at Washington University School of Medicine in St. Louis. […]
Research
Study prompts new ideas on cancers’ origins
Rapidly dividing, yet aberrant stem cells are a major source of cancer. But a new study suggests that mature cells also play a key role in initiating cancer — a finding that could upend the way scientists think about the origins of the disease. Researchers at Washington University School of Medicine in St. Louis have […]
In the Media, Research, Staff/Faculty Update
Undaunted explorer
Timothy Ley, MD, the Lewis T. and Rosalind B. Apple Professor of Medicine, has been investigating leukemia, particularly acute myeloid leukemia (AML), for decades. A glimpse of his research over just the past 10 to 15 years — featured in journals like Nature, Cell, the New England Journal of Medicine and Journal of the American Medical Association — illustrates how challenging […]
Research, Staff/Faculty Update
$6 million supports leukemia research
John F. DiPersio, MD, PhD, of Washington University School of Medicine in St. Louis, has received a $6 million outstanding investigator award from the National Cancer Institute (NCI) of the National Institutes of Health (NIH) to support research aimed at improving therapies for leukemia. DiPersio, the Virginia E. and Sam J. Golman Professor of Medicine […]