News & Breakthroughs at Siteman
Stay informed with the latest cancer news and breakthroughs from Siteman Cancer Center. Our news feed provides timely updates on research breakthroughs, clinical trials, and community events.
Research News & Stories
Research
Light-triggered nanoparticles show promise against metastatic cancer
A new anti-cancer strategy wields light as a precision weapon. Unlike traditional light therapy — which is limited to the skin and areas accessible with an endoscope — this technique can target and attack cancer cells that have spread deep inside the body, according to researchers at Washington University School of Medicine in St. Louis. […]
Research
Study prompts new ideas on cancers’ origins
Rapidly dividing, yet aberrant stem cells are a major source of cancer. But a new study suggests that mature cells also play a key role in initiating cancer — a finding that could upend the way scientists think about the origins of the disease. Researchers at Washington University School of Medicine in St. Louis have […]
In the Media, Research, Staff/Faculty Update
Undaunted explorer
Timothy Ley, MD, the Lewis T. and Rosalind B. Apple Professor of Medicine, has been investigating leukemia, particularly acute myeloid leukemia (AML), for decades. A glimpse of his research over just the past 10 to 15 years — featured in journals like Nature, Cell, the New England Journal of Medicine and Journal of the American Medical Association — illustrates how challenging […]
Research, Staff/Faculty Update
$6 million supports leukemia research
John F. DiPersio, MD, PhD, of Washington University School of Medicine in St. Louis, has received a $6 million outstanding investigator award from the National Cancer Institute (NCI) of the National Institutes of Health (NIH) to support research aimed at improving therapies for leukemia. DiPersio, the Virginia E. and Sam J. Golman Professor of Medicine […]
Research
How cells detect, mend DNA damage may improve chemotherapy
The busy world inside a cell is directed by its DNA blueprint. When the blueprints are altered, cells can sicken, die or become cancerous. To keep DNA in working order, cells have ways to detect and mend damaged DNA. Now, researchers at Washington University School of Medicine in St. Louis report that they have found […]
Research
Chemo-loaded nanoparticles target breast cancer that has spread to bone
Breast cancer that spreads often infiltrates bone, causing fractures and intense pain. In such cases, chemotherapy is ineffective because the environment of the bone protects the tumor, even as the drug has toxic side effects elsewhere in the body. Now, scientists at Washington University School of Medicine in St. Louis have developed a nanoparticle that […]
Research
Surgery for early prostate cancer may not save lives
A major 20-year study provides further evidence that prostate cancer surgery offers negligible benefits to many men with early-stage disease. In such men, who account for most cases of newly diagnosed prostate cancer, surgery did not prolong life and often caused serious complications such as infection, urinary incontinence and erectile dysfunction. The study, by a […]
Research
Zika virus kills brain cancer stem cells
While Zika virus causes devastating damage to the brains of developing fetuses, it one day may be an effective treatment for glioblastoma, a deadly form of brain cancer. New research from Washington University School of Medicine in St. Louis and the University of California San Diego School of Medicine shows that the virus kills brain […]
Research
New imaging technique aims to ensure surgeons completely remove cancer
Of the quarter-million women diagnosed with breast cancer every year in the United States, about 180,000 undergo surgery to remove the cancerous tissue while preserving as much healthy breast tissue as possible. However, there’s no accurate method to tell during surgery whether all of the cancerous tissue has been successfully removed. The gold-standard analysis takes a […]
Research
Online database aims to collect, organize research on cancer mutations
The body of knowledge on cancer genomics is massive and ever-expanding. But this wealth of potentially critical information is far less likely to be of help to patients if it is inaccessible to the doctors who treat them. Researchers at Washington University School of Medicine in St. Louis have developed an online “knowledgebase” intended for […]