News & Breakthroughs at Siteman
Stay informed with the latest cancer news and breakthroughs from Siteman Cancer Center. Our news feed provides timely updates on research breakthroughs, clinical trials, and community events.
Research News & Stories
Research
Sex differences identified in deadly brain tumors
For decades, scientists have recognized that more males get cancer and die of the disease than females. This is true for many types of cancer, including the deadly brain tumor glioblastoma. Now, a team of researchers led by Washington University School of Medicine in St. Louis has identified distinct molecular signatures of glioblastoma in men […]
In the Media, Research
$5 million supports innovative breast cancer trial at Siteman
A $5 million grant from the Department of Defense will support research at Washington University School of Medicine in St. Louis aimed at improving breast cancer therapies. The study, which includes a clinical trial at Siteman Cancer Center at Barnes-Jewish Hospital and the School of Medicine, will focus on HER2-positive breast cancer. Such tumors are dotted with an overabundance […]
Research
Brain cancer vaccine effective in some patients
Most people with the deadly brain cancer glioblastoma die less than 18 months after diagnosis. But a multicenter clinical trial of a personalized vaccine that targets the aggressive cancer has indicated improved survival rates for such patients. The study appears May 29 in the Journal of Translational Medicine. The phase three clinical trial included 331 […]
Research
Experimental arthritis drug prevents stem cell transplant complication
An investigational drug in clinical trials for rheumatoid arthritis prevents a common, life-threatening side effect of stem cell transplants, new research from Washington University School of Medicine in St. Louis shows. Studying mice, the researchers found the drug prevented what’s known as graft-versus-host disease, a debilitating, sometimes lethal condition that develops when transplanted stem cells […]
Research
For women with kidney cancer, belly fat matters
Belly fat affects the odds of women surviving kidney cancer but not men, according to a new study by researchers at Washington University School of Medicine in St. Louis. Half of female kidney cancer patients with substantial abdominal fat at the time of diagnosis died within 3 1/2 years, while more than half of women […]
Research
Major milestone reached in effort to ID cancers’ genetic roots
Researchers nationwide have reached a major milestone in describing the genetic landscape of cancer. Scientists at Washington University School of Medicine in St. Louis and other institutions have completed the genetic sequencing and analyses of more than 11,000 tumors from patients, spanning 33 types of cancer — all part of The Cancer Genome Atlas (TCGA) […]
Research
CRISPR enhances cancer immunotherapy
Last year, the Food and Drug Administration approved the first cellular immunotherapies to treat cancer. These therapies involve collecting a patient’s own immune cells — called T cells — and supercharging them to home in on and attack specific blood cancers, such as hard-to-treat acute lymphoblastic leukemia and non-Hodgkin lymphoma. But so far, these T […]
Research
Higher doses of radiation don’t improve survival in prostate cancer
A new study shows that higher doses of radiation do not improve survival for many patients with prostate cancer, compared with the standard radiation treatment. The analysis, which included 104 radiation therapy oncology groups across North America, was led by researchers at Washington University School of Medicine in St. Louis. Past studies have shown that […]
Research
Cutting off cervical cancer’s fuel supply stymies tumor
Cancer therapies have improved — in some cases dramatically — over the past two decades, but treatment for cervical cancer has remained largely unchanged. All patients receive radiation and chemotherapy, yet despite the aggressive approach, the regimen fails in about one-third of patients with cervical cancer that has spread beyond the cervix but not outside […]
Research
Similarities found in cancer initiation in kidney, liver, stomach, pancreas
Recent research at Washington University School of Medicine in St. Louis demonstrated that mature cells in the stomach sometimes revert back to behaving like rapidly dividing stem cells. Now, the researchers have found that this process may be universal; no matter the organ, when tissue responds to certain types of injury, mature cells seem to […]