Gwendalyn Randolph, PhD

Research Program Tumor Immunology
Gwendalyn Randolph

Researcher Background

Primary Academic Title

Emil R. Unanue Distinguished Professor of Medicine, Department of Pathology and Immunology; Director, Immunology Graduate Program, WashU Medicine

Training

  • 1995 - 1996: Postdoctoral Fellow, Cellular Physiology and Immunology, The Rockefeller University, New York, NY
  • 1997 - 1998: Postdoctoral Associate, Pathology, Cornell University, New York, NY

Education

  • 1995: PhD, Cellular and Molecular Pathology, State University of New York at Stony Brook, Stony Brook, NY

Research & Selected Publications

Research Interest

Tissue macrophages; immune cell migration; lymphatic vessels and lymphoid tissue; immunology of the peritoneal cavity

Research Publications

Lymphatic disruption drives lung transplant fibrosis through interleukin-1-mediated hyaluronan accumulation.
Authors:

Shepherd HM, Li W, Kopecky BJ, one or more additional authors omitted Randolph GJ, Kreisel D

Journal & Year:

Sci Transl Med • 2026

Transcription factor Maf promotes expression of repressor Zeb2 to drive microglia development in primitive hematopoiesis.
Authors:

Chen J, Du S, Cheng W, one or more additional authors omitted Randolph GJ, one or more additional authors omitted Murphy KM

Journal & Year:

Immunity • 2026

Adipocytes are dispensable in shaping the ovarian cancer tumor microenvironment in the omentum.
Authors:

Mintz RL, Han J, Butka EG, one or more additional authors omitted Randolph GJ

Journal & Year:

bioRxiv • 2025

Distinct roles for B cell-derived LTα3 and LTα1β2 in TNF-mediated ileitis.
Authors:

Erlich EC, Alayo QA, Kim A, one or more additional authors omitted Randolph GJ

Journal & Year:

Nat Immunol • 2025

ADAPT-3D:accelerated deep adaptable processing of tissue for 3-dimensional fluorescence tissue imaging for research and clinical settings.
Authors:

Lee DD, Telfer KA, Davis DL, one or more additional authors omitted Randolph GJ

Journal & Year:

Sci Rep • 2025

Lymphatic mysteries unzipped.
Authors:

Petrova TV, Randolph GJ

Journal & Year:

Nat Cardiovasc Res • 2025

Tracing LYVE1+ peritoneal fluid macrophages unveils two paths to resident macrophage repopulation with differing reliance on monocytes.
Authors:

Gallerand A, Han J, Mintz RL, one or more additional authors omitted Randolph GJ

Journal & Year:

bioRxiv • 2025

A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control.
Authors:

Wang Y, Zhang Y, Kim K, one or more additional authors omitted Randolph GJ, one or more additional authors omitted Benoist C

Journal & Year:

Immunity • 2024