Hussein Sultan, PhD

Research Program Tumor Immunology
Hussein Sultan

Researcher Background

Primary Academic Title

Assistant Professor, Department of Pathology & Immunology, WashU Medicine

Training

  • 2018 - 2023: Postdoctoral Research Scholar, Robert Schreiber Lab, Department of Pathology and Immunology, Washington University, St. Louis, MO

Education

  • 2008: BSPS, School of Pharmacy, Cairo University, Cairo, Egypt
  • 2017: PhD, Augusta University/Medical College of Georgia, Augusta, GA

Research & Selected Publications

Research Interest

My utmost motivation lies in enhancing the safety and effectiveness of cancer immunotherapy, with specific emphasis on personalized neoantigen cancer vaccines. My research focuses on two main areas: 1-Define the intrinsic and extrinsic factors that lead to the induction/development of type 1 regulatory T cells and unravel the mechanisms involved in their suppressive activity. 2-Develop novel vaccination strategies that promote the induction of effector anti-tumor T cells while avoiding the generation of suppressive T-cell responses that promote tumor progression.

Research Publications

Cancer Neoantigen Vaccines Emerge Efficacious.
Authors:

Sultan H, Schreiber RD

Journal & Year:

Annu Rev Med • 2026

Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy.
Authors:

Sultan H, Takeuchi Y, Ward JP, one or more additional authors omitted Schreiber RD

Journal & Year:

Nature • 2024

IL2 Targeted to CD8+ T Cells Promotes Robust Effector T-cell Responses and Potent Antitumor Immunity.
Authors:

Moynihan KD, Kumar MP, Sultan H, one or more additional authors omitted Djuretic IM

Journal & Year:

Cancer Discov • 2024