Jeffrey Gordon, MD

Medical School Department Biology
Research Program Solid Tumor Therapeutics
Jeffrey Gordon

Researcher Background

Primary Academic Title

Dr. Robert J. Glaser Distinguished University Professor of Developmental Biology, WashU Medicine

Training

  • 1973 - 1975: Intern and Resident, Internal Medicine, WashU Medicine, St. Louis, MO
  • 1975 - 1978: Research Associate, Molecular Biology, National Cancer Institute, Bethesda, MD
  • 1978 - 1979: Resident, Internal Medicine, WashU Medicine, St. Louis, MO
  • 1979 - 1981: Fellow, Gastroenterology, WashU Medicine, St. Louis, MO

Education

  • 1973: MD, University of Chicago, Chicago, IL

Research & Selected Publications

Research Interest

We have three projects related to cancer: a gnotobiotic transgenic mouse model to study the molecular features of gastric stem cells and the effect of attachment of Helicobacter pylori to these epithelial progenitors on gastric tumorigenesis; a transgenic mouse model of metastatic prostate cancer to examine initiation and progression of neuroendocrine cancers in general and CaP in particular; and biochemical, biophysical and genetic approaches and yeast as a model organism to study the regulation of protein N-myristoylation and its biological significance.

Research Publications

TREM2 deficiency reprograms intestinal macrophages and microbiota to enhance anti-PD-1 tumor immunotherapy.
Authors:

Di Luccia B, Molgora M, Khantakova D, one or more additional authors omitted Gordon JI, Colonna M

Journal & Year:

Sci Immunol • 2024