Marina Cella, MD

Medical School Department Pathology and Immunology
Research Program Tumor Immunology
Marina Cella

Researcher Background

Primary Academic Title

Professor of Pathology and Immunology, WashU Medicine

Training

  • 1989 - 1993: Fellow, Immunogenetics, National Institute for Cancer Research, Genova, Italy

Education

  • 1989: MD, University of Genova School of Medicine, Genova, Italy

Research & Selected Publications

Research Interest

My interest focuses on Type 3 Innate Lymphoid Cells (ILC3) present at mucosal sites. The cell type depends on the transcription factor Aryl Hydrocarbon Receptor (AHR) for development, maintenance and function. I’m interested in understanding whether AHR ligands (agonist/antagonist) modulate ILC3 during obesity and whether this affects colon cancer development.

Research Publications

Establishment of a reverse genetics system for studying human immune functions in mice.
Authors:

Pal P, Gao S, Gao H, one or more additional authors omitted Cella M, one or more additional authors omitted Shan L

Journal & Year:

Sci Adv • 2025

Multidimensional profiling of human T cells reveals high CD38 expression, marking recent thymic emigrants and age-related naive T cell remodeling.
Authors:

Bohacova P, Terekhova M, Tsurinov P, one or more additional authors omitted Cella M, one or more additional authors omitted Artyomov MN

Journal & Year:

Immunity • 2024

Diversity of group 1 innate lymphoid cells in human tissues.
Authors:

Jaeger N, Antonova AU, Kreisel D, one or more additional authors omitted Cella M, Colonna M

Journal & Year:

Nat Immunol • 2024

Progenitors of distinct lineages shape the diversity of mature type 2 conventional dendritic cells.
Authors:

Rodrigues PF, Trsan T, Cvijetic G, one or more additional authors omitted Cella M, Colonna M

Journal & Year:

Immunity • 2024

TREM2 deficiency reprograms intestinal macrophages and microbiota to enhance anti-PD-1 tumor immunotherapy.
Authors:

Di Luccia B, Molgora M, Khantakova D, one or more additional authors omitted Cella M, one or more additional authors omitted Colonna M

Journal & Year:

Sci Immunol • 2024

The transcription factor Aiolos restrains the activation of intestinal intraepithelial lymphocytes.
Authors:

Yomogida K, Trsan T, Sudan R, one or more additional authors omitted Cella M, one or more additional authors omitted Colonna M

Journal & Year:

Nat Immunol • 2024