Michael Onken, PhD

Medical School Department Cell Biology and Physiology
Research Program Mechanisms of Cancer Biology Program
Michael Onken

Researcher Background

Primary Academic Title

Associate Professor of Cell Biology and Physiology, WashU Medicine

Training

  • 2003 - 2012: Postdoctoral Fellow and Research Assistant, Ophthalmology, WashU Medicine, St. Louis, MO

Education

  • 2000: PhD, Molecular Cell Biology, WashU Medicine, St. Louis, MO

Research & Selected Publications

Research Interest

Mechanisms of metastatic spread of cancer to distant organs; specifically, the genetic and cytoskeletal factors that control migration and motility in melanoma cells.

Reserach Publications

Inositol (1,4,5)-trisphosphate 5-phosphatase promotes survival of uveal melanoma by regulating oncogenic G protein-driven calcium oscillations.
Authors:

Onken MD, Makepeace CM, Kaltenbronn KM, one or more additional authors omitted Blumer KJ

Journal & Year:

J Biol Chem • 2025

Protein Kinase Signaling Networks Driven by Oncogenic Gq/11 in Uveal Melanoma Identified by Phosphoproteomic and Bioinformatic Analyses.
Authors:

Onken MD, Erdmann-Gilmore P, Zhang Q, one or more additional authors omitted Blumer KJ

Journal & Year:

Mol Cell Proteomics • 2023