Julius Chembo View Appointment Options Julius Chembo Appointment Options Research & Selected Publications Share Copy Link Email Link Print Page Facebook X Instagram LinkedIn Back Gmail Outlook Apple Mail Yahoo! Mail Appointment Options Whether you’re seeking a new patient appointment or exploring treatment options and looking for a second opinion, our Siteman care coordinators are ready to assist you. Request an Appointment Call Us Refer a Patient Research & Selected Publications Pyrimethamine and a potent analog inhibit NRF2 by suppressing one-carbon metabolism Pyrimethamine and a potent analog inhibit NRF2 by suppressing one-carbon metabolism Authors: Chembo J, Bowman BM, Lapak K, [...]one or more additional authors omitted Major MB Journal & Year: J Biol Chem | 2025 Pyrimethamine and a potent analogue WCDD115 inhibit NRF2 by suppressing DHFR and one-carbon metabolism Pyrimethamine and a potent analogue WCDD115 inhibit NRF2 by suppressing DHFR and one-carbon metabolism Authors: Chembo J, Bowman BM, Lapak K, [...]one or more additional authors omitted Major MB Journal & Year: bioRxiv | 2025 Small molecule screen identifies pyrimethamine as an inhibitor of NRF2-driven esophageal hyperplasia Small molecule screen identifies pyrimethamine as an inhibitor of NRF2-driven esophageal hyperplasia Authors: Paiboonrungruang C, Xiong Z, Lamson D, [...]one or more additional authors omitted Chembo J, [...]one or more additional authors omitted Chen X Journal & Year: Redox Biol | 2023