Clair Crewe, PhD

Research Program Breast Cancer Research
Clair Crewe

Researcher Background

Primary Academic Title

Assistant Professor, Department of Cell Biology and Physiology, Department of Innternal medicine, Division of Endocrinology, Metabolism and Lipid Research, WashU Medicine

Training

  • 2015 - 2019: Postdoctoral Fellow, University of Texas Southwestern Medical Center, Dallas, TX

Education

  • 2009: BS, Oklahoma Christian University, Edmond, OK
  • 2015: PhD, University of Oklahoma Health Sciences Center, Oklahoma City, OK

Research & Selected Publications

Research Interest

The Crewe lab is interested in how extracellular vesicles (EVs) mediate signaling between cells in the tumor microenvironment. EVs are nano-sized vesicles that carry biomolecules like RNAs, metabolites, and signaling proteins that have been shown to regulate cancer progression and immune evasion. Our focus is on how EV signaling may affect tumor suppressor function in breast cancer.

Research Publications

Immune cells regulate circulating adipocyte extracellular vesicle levels in response to metabolic shifts.
Authors:

Tiash S, Patel SA, Russo M, one or more additional authors omitted Crewe C

Journal & Year:

Cell Metab • 2026

Immune cells regulate circulating adipocyte extracellular vesicle levels in response to metabolic shifts.
Authors:

Tiash S, Russo M, Pai YL, one or more additional authors omitted Crewe C

Journal & Year:

bioRxiv • 2025