Brief Summary
This study is being done to answer the following question: can the chance of prostate cancer growing or spreading be lowered by adding a drug to the usual combination of drugs>=
This study would like to find out if this approach is better or worse than the usual approach for prostate cancer.
The usual approach for patients who are not in a study is hormone treatment with Androgen Deprivation Therapy (ADT) and Androgen-Receptor Pathway Inhibitor (ARPI).
Protocol Interventions
Drug: Abiraterone, Drug: Enzalutamide, Drug: Apalutamide, Drug: Darolutamide (BAY 1841788), Drug: Docetaxel, Drug: ADT