Michael Gross, PhD

Medical School Department Chemistry
Research Program Oncologic Imaging
Michael Gross

Researcher Background

Primary Academic Title

Professor of Chemistry, WashU Medicine

Training

  • 1966 - 1967: Post-Doctoral Fellow, Organic Chemistry, University of Pennsylvania, Philadelphia, PA
  • 1967 - 1968: Postdoctoral Fellow, Mass Spectrometry, Purdue University, West Lafayette, IN

Education

  • 1966: PhD, Organic Chemistry, University of Minnesota, MN

Research & Selected Publications

Research Interest

Development of methods for modified DNA; biomarkers of cancer; proteomics.

Research Publications

A SWI/SNF-specific Ig-like domain, SWIFT, is a transcription factor binding platform.
Authors:

Jain SU, Williamson KE, Ying AW, one or more additional authors omitted Gross ML, Kadoch C

Journal & Year:

Science • 2026

In-Cell Fast Photochemical Oxidation Interrogates the Native Structure of Integral Membrane Proteins.
Authors:

Sun J, Saimi M, Rempel D, one or more additional authors omitted Gross ML

Journal & Year:

Angew Chem Int Ed Engl • 2025

Kingfisher: An open-sourced web-based platform for the analysis of hydrogen exchange mass spectrometry data.
Authors:

McLaughlin NK, Rincon Pabon JP, Gies S, Dastvan R, Gross ML

Journal & Year:

Protein Sci • 2025

Mass Spectrometry-Based Protein Footprinting for Protein Structure Characterization.
Authors:

Cheng M, Gross ML

Journal & Year:

Acc Chem Res • 2025

Distinguishing Isomeric Cyclobutane Thymidine Dimers by Ion Mobility and Tandem Mass Spectrometry.
Authors:

Yang HC, Scruggs SS, Chai M, one or more additional authors omitted Gross ML

Journal & Year:

J Am Soc Mass Spectrom • 2024

Evaluating Chemical Footprinting-Induced Perturbation of Protein Higher Order Structure.
Authors:

Wagner WJ, Moyle AB, Wagner ND, Rempel DL, Gross ML

Journal & Year:

Anal Chem • 2024

Precursor Reagent Hydrophobicity Affects Membrane Protein Footprinting.
Authors:

Guo C, Cheng M, Li W, Gross ML

Journal & Year:

J Am Soc Mass Spectrom • 2023

Characterization of Higher Order Structural Changes of a Thermally Stressed Monoclonal Antibody via Mass Spectrometry Footprinting and Other Biophysical Approaches.
Authors:

Lin Y, Moyle AB, Beaumont VA, one or more additional authors omitted Gross ML

Journal & Year:

Anal Chem • 2023