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Research & Selected Publications

Transcription factor Maf promotes expression of repressor Zeb2 to drive microglia development in primitive hematopoiesis
Authors:

Chen J, Du S, Cheng W, one or more additional authors omitted Murphy TL, Murphy KM

Journal & Year:

Immunity | 2026

The Making of a cDC1: Precision Programming of Progenitor Potential
Authors:

Murphy TL, Murphy KM

Journal & Year:

Immunol Rev | 2026

C/EBPα activates Irf8 expression in myeloid progenitors at the +56-kb enhancer to initiate cDC1 development
Authors:

Chen J, Liu TT, Ou F, one or more additional authors omitted Murphy TL, one or more additional authors omitted Kim S

Journal & Year:

Sci Immunol | 2025

Shared pathway of WDFY4-dependent cross-presentation of immune complexes by cDC1 and cDC2
Authors:

Jo S, Ohara RA, Theisen DJ, one or more additional authors omitted Murphy TL, Murphy KM

Journal & Year:

J Exp Med | 2025

Optimization of the Irf8 +32-kb enhancer disrupts dendritic cell lineage segregation
Authors:

Ou F, Liu TT, Desai P, one or more additional authors omitted Murphy TL, Murphy KM

Journal & Year:

Nat Immunol | 2024

IL-6 selectively suppresses cDC1 specification via C/EBPβ
Authors:

Kim S, Chen J, Jo S, one or more additional authors omitted Murphy TL, Murphy KM

Journal & Year:

J Exp Med | 2023