Washington University Center for Cellular Imaging (WUCCI)

LEADERSHIP: Eduardo Rosa-Molinar, PhD

The Washington University Center for Cellular Imaging (WUCCI) shared resource (SR) offers carefully managed, cost-effective access to advanced light microscopy (LM), electron microscopy (EM), cryo-electron microscopy (cryo-EM), cryo-electron tomography (cryo-ET) workflows, and integrated analytics. Located in a purpose-built facility, WUCCI provides seamless pipelines and computational analysis for multiscale structural and functional imaging of human tumors, organoids, assembloids, and preclinical models. By combining light sheet fluorescence microscopy (LSFM), super-resolution fluorescence microscopy (SRFM), correlated light and electron microscopy (CLEM), volume electron microscopy (vEM), cryo-EM, cryo-ET, and computational pipelines, WUCCI enables Siteman members to study cancer at organelle-to-tissue scales with detailed quantitative analysis, reproducibility, and scientific rigor.

LOCATION: Couch Biomedical Research Building, 4515 McKinley Ave., St. Louis, MO 63110

PRICING: Rates available here: https://wucci.wustl.edu/user-info/rates/. CCSG members receive a 25% across-the-board rate subsidy.

TO ACCESS: Please call 314-747-0838 or visit WUCCI’s website: https://wucci.wustl.edu/

NIH PUBLIC ACCESS POLICY: As of April 7, 2008, the NIH requires investigators with a publication using Siteman (or other NIH-funded) shared resources to submit (or have submitted for them) their final, peer reviewed manuscripts to PubMed Central(PMC) upon acceptance of publication, to be made publicly available within 12 months of publication. Many journals automatically submit these for authors, but Washington University also has assistance available through the Becker Medical Library. Please see this resource for more information.

PUBLICATION ACKNOWLEDGEMENT: If research supported by the Genome Engineering and Induced Pluripotent Stem Cell Center results in publication, please acknowledge this support by including the following in your publication(s):

We thank the Alvin J. Siteman Cancer Center at Washington University School of Medicine and Barnes-Jewish Hospital in St. Louis, MO., for the use of the Genome Engineering and Induced Pluripotent Stem Cell Center, which provided __________ service. The Siteman Cancer Center is supported in part by an NCI Cancer Center Support Grant #P30 CA091842.